Research on this topic comes mostly from observational studies and smaller clinical trials. Results vary widely, but here are five areas where differences often appear.
5. Stress and Mood Can Feel Harder to Manage
Sex is a powerful natural stress reliever. Orgasm and physical closeness spike endorphins and oxytocin while lowering cortisol (the stress hormone). Without that outlet, some people report higher daily anxiety, irritability, or even mild depressive symptoms.
But here’s the good news: many find alternative stress-relief methods—exercise, meditation, deep breathing—just as effective. Still, for couples, reigniting intimacy often brings back that effortless emotional lift.
4. Your Immune System Might Miss a Small Boost
A frequently cited study from Wilkes University found that college students having sex 1–2 times per week had higher levels of salivary immunoglobulin A (IgA), an antibody that helps fight off colds and infections, compared to those having little or no sex.
The difference wasn’t dramatic, and larger studies are needed. Yet the hormonal shifts during intimacy seem to give the immune system a gentle workout. Long-term abstinence doesn’t mean you’ll get sick more often—lifestyle factors like sleep and diet matter far more—but some research hints at a modest edge from moderate activity.
3. Cardiovascular Health Benefits May Fade
