Popular drugs have been found to have side effects, what are they?

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The drugs reduced the total volume of the gut microbiota, damaged biodiversity, and killed microorganisms that normally compete with pathogens for nutrients. As a result, the microbiome itself was altered, creating a more favorable environment for pathogens to thrive. The study authors emphasize that these effects can be dangerous for the elderly and frail.

Scientists recommend testing the effect of drugs on the microbiome when developing new medications, including antihistamines, antipsychotics, or selective estrogen receptor modulators (used to treat osteoporosis, breast cancer, and stimulate ovulation), as well as when combining multiple drugs. Technology has also been developed to test the effect of drugs on microbiome stability.